Mr. Osato was the fictional head of Osato Chemicals and Engineering and an associate of SPECTRE. The character appeared as the central antagonist in the 1967 James Bond film You Only Live Twice and was portrayed by Teru Shimada.
When the movie got dubbed in Japanese, Osato was voiced by Yuzuru Fujimoto and Jin Urayama in the TBS and DVD/Blu-Ray versions, respectively.
When James Bond follows an assassin of his Japanese contact Dikko Henderson, he goes to Osato's company and finds a safe that tells him a few things, namely a large order for "lox". Though mistaken for fish, Tiger Tanaka deduces that "lox" is shorthand for "liquid oxygen", a component used in rocket fuel, and as such Osato must be supplying Blofeld with fuel. Posing as Mr. Fisher from the British company Empire Chemicals, Bond pretends to be interested in a contract with Osato Chemicals. He is warmly greeted by Mr. Osato and Helga Brandt, his glamorous henchwoman and SPECTRE No.11. However, Osato knows the truth and then orders his men to kill Bond, who escapes thanks to Aki. Osato then captures Bond, and leaves him with Helga, for her to kill. But the beautiful young woman allows herself to have sex with 007, and Bond manages to survive again.
Ernst Stavro Blofeld then summons Osato and Brandt to his quarters for an urgent report, and reprimands them for failing to kill Bond. Blofeld gives Osato and Brandt the strictest order to kill Bond; however, Osato, without any leniency for his henchwoman, puts the whole blame on Helga for her to be punished alone. Blofeld decides to execute Helga Brandt for her failure in an horrible way by plunging her in a pool full of piranhas where she dies eaten alive, screaming for Osato’s help before being ripped to the bones. Osato is then ordered to kill Bond if he doesn’t want to get the same awful fate. Osato then attempts to kill Bond by using a fake ninja who has a knife but Bond outsmarts him. The other way is by dropping poison into his mouth while he is asleep, which because he turned over, killed Aki instead. Both these attempts were carried out by his henchmen, and Osato is at the end scene. Bond is captured by Osato and Blofeld, after his attempt to infiltrate the SPECTRE Volcano. Blofeld takes his gun and points it at Bond, saying "This is the price of failure, Mr. Bond," but then he turns the gun and shoots Osato instead.